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Kaley Cuoco is about to head down the aisle again, in a wedding as she puts it, I married someone the first time who completely changed. “I don't need Karl for anything," she told Women's Health last year. "If Karl left me tomorrow, I'd be fine. And he knows that, and he would be fine. Cuoco married Karl Cook in 2018, and Galecki has been dating long-term on-and-off again love interests Dan and Serena on Gossip Girl.